SCHEMBL18079764

NC(=O)CC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ERAP2	Q6P179	2/20	0.57

▸	GHSR	Q92847	3/20	0.55

▸	LTA4H	P09960	1/20	0.54

▸	NPY1R	P25929	3/20	0.53

▸	NPY2R	P49146	3/20	0.53

▸	NPY4R	P50391	3/20	0.53

▸	IL1RN	P18510	1/20	0.52

▸	ERAP1	Q9NZ08	1/20	0.52

▸	ACE	P12821	1/20	0.51

▸	MME	P08473	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17877082	1.00	ERAP2 (0.57)	ERAP2GHSRLTA4HNPY1RNPY2R
SCHEMBL18256998	1.00	ERAP2 (0.57)	ERAP2GHSRLTA4HNPY1RNPY2R
SCHEMBL30284429	0.94	ERAP2 (0.64)	ERAP2LTA4HACE
SCHEMBL17941661	0.94	LTA4H (0.59)	ERAP2GHSRLTA4HNPY1RNPY2R
SCHEMBL17941660	0.94	LTA4H (0.59)	ERAP2GHSRLTA4HNPY1RNPY2R
SCHEMBL17880376	0.93	GHSR (0.57)	ERAP2GHSRNPY1RNPY2RNPY4R
SCHEMBL14552702	0.93	GHSR (0.57)	ERAP2GHSRNPY1RNPY2RNPY4R
SCHEMBL14553988	0.93	GHSR (0.57)	ERAP2GHSRNPY1RNPY2RNPY4R
SCHEMBL31485778	0.93	ERAP2 (0.57)	ERAP2GHSRLTA4HACEMME
SCHEMBL18257005	0.93	ERAP2 (0.57)	ERAP2GHSRLTA4HNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9447151-B2	Beta sheet tapes ribbons in tissue engineering	THE UNIVERSITY OF LEEDS (GB)	2016-09-20	—	—	US	disclosed
US-9447151-B2	Beta sheet tapes ribbons in tissue engineering	THE UNIVERSITY OF LEEDS (GB)	2016-09-20	—	—	US	disclosed