Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.57 |
| ▸ | GHSR | Q92847 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 3/20 | 0.53 |
| ▸ | NPY2R | P49146 | 3/20 | 0.53 |
| ▸ | NPY4R | P50391 | 3/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079764 | 1.00 | ERAP2 (0.57) | ERAP2GHSRLTA4HNPY1RNPY2R | |
| SCHEMBL17877082 | 1.00 | ERAP2 (0.57) | ERAP2GHSRLTA4HNPY1RNPY2R | |
| SCHEMBL30284429 | 0.94 | ERAP2 (0.64) | ERAP2LTA4HACE | |
| SCHEMBL17941661 | 0.94 | LTA4H (0.59) | ERAP2GHSRLTA4HNPY1RNPY2R | |
| SCHEMBL17941660 | 0.94 | LTA4H (0.59) | ERAP2GHSRLTA4HNPY1RNPY2R | |
| SCHEMBL17880376 | 0.93 | GHSR (0.57) | ERAP2GHSRNPY1RNPY2RNPY4R | |
| SCHEMBL14552702 | 0.93 | GHSR (0.57) | ERAP2GHSRNPY1RNPY2RNPY4R | |
| SCHEMBL14553988 | 0.93 | GHSR (0.57) | ERAP2GHSRNPY1RNPY2RNPY4R | |
| SCHEMBL31485778 | 0.93 | ERAP2 (0.57) | ERAP2GHSRLTA4HACEMME | |
| SCHEMBL18257005 | 0.93 | ERAP2 (0.57) | ERAP2GHSRLTA4HNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160340392-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2016-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340392-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, TAGLN2, KRT18 | ERAP2 524/4885GHSR 3289/4885LTA4H 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.