Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 7/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318146 | 0.87 | AR (0.31) | CACNA1HCYP11B2AR | |
| SCHEMBL1807378 | 0.87 | AR (0.46) | AR | |
| SCHEMBL319182 | 0.86 | BACE1 (0.36) | CACNA1HCYP11B2CYP11B1 | |
| SCHEMBL318455 | 0.85 | CACNA1H (0.37) | CACNA1HCYP11B2CYP11B1AREGLN2 | |
| SCHEMBL12653559 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL1805279 | 0.80 | RXRB (0.44) | — | |
| SCHEMBL13635923 | 0.79 | CRHR1 (0.35) | — | |
| SCHEMBL17512337 | 0.79 | MKNK1 (0.37) | — | |
| SCHEMBL807501 | 0.79 | ALOX5AP (0.31) | — | |
| SCHEMBL926339 | 0.79 | NOTUM (0.34) | CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | DDT, LAP3, CYP4X1 | CACNA1H 2063/4885CYP11B2 3684/4885CYP11B1 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.