Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909995 | 1.00 | SQOR (0.53) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7905799 | 0.85 | ASAH1 (0.72) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7915776 | 0.85 | ASAH1 (0.72) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7917602 | 0.85 | ASAH1 (0.72) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7905795 | 0.85 | ASAH1 (0.72) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL12104154 | 0.85 | ASAH1 (0.72) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7919650 | 0.84 | LMNA (0.46) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7910033 | 0.84 | LMNA (0.46) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11626192 | 0.83 | SQOR (0.71) | SQORLMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11632037 | 0.83 | SQOR (0.71) | SQORLMNACYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46144-E1 | Hydroxamic acid derivatives | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2016-09-13 | — | — | US | disclosed |