Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12104154 | 1.00 | ASAH1 (0.72) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7917602 | 1.00 | ASAH1 (0.72) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7905799 | 1.00 | ASAH1 (0.72) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7915776 | 1.00 | ASAH1 (0.72) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL29001286 | 0.88 | ASAH1 (0.75) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL18325592 | 0.85 | ASAH1 (0.75) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL9775183 | 0.85 | ASAH1 (0.79) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL7909995 | 0.85 | SQOR (0.53) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL18082002 | 0.85 | SQOR (0.53) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL10933495 | 0.84 | ASAH1 (1.00) | ASAH1LMNACYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46144-E1 | Hydroxamic acid derivatives | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2016-09-13 | — | — | US | disclosed |
| US-9096627-B2 | Hydroxamic acid derivatives | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140066419-A1 | HYDROXAMIC ACID DERIVATIVES | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2014-03-06 | — | — | US | disclosed |
| US-20110269706-A1 | Hydroxamic Acid Derivatives | NORTHLAKE BIOSCIENCES LLC (US) | 2011-11-03 | — | — | US | disclosed |
| WO-2010085377-A2 | HYDROXAMIC ACID DERIVATIVES | CRYSTAL BIOPHARMACEUTICAL LLC (US) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066419-A1 | HYDROXAMIC ACID DERIVATIVES | HDAC5, HDAC7, HDAC4 | ASAH1 24/4885LMNA 2696/4885CYP3A4 4223/4885 |
| US-20110269706-A1 | Hydroxamic Acid Derivatives | CD74, HLA-DRB1, HDAC5 | ASAH1 84/4885LMNA 3497/4885CYP3A4 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.