Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9282683 | 0.86 | GAA (0.60) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL9292476 | 0.84 | ALOX5 (0.59) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL1708401 | 0.81 | GAA (0.58) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL10786189 | 0.81 | ALOX5 (0.55) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL724655 | 0.81 | PTGS1 (0.51) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL722951 | 0.81 | GAA (0.54) | ALOX5PTGS1PTGS2LMNARECQL | |
| Hydrochloric Acid SCHEMBL10786981 | 0.80 | ALOX5 (0.54) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL1928189 | 0.79 | LMNA (0.61) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL47590 | 0.79 | LMNA (0.55) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL2481839 | 0.78 | ALOX5 (0.55) | ALOX5PTGS1PTGS2LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751084-B1 | PYRIMIDINE CARBOXAMIDE DERIVATIVES | EUDIS BIOTECH LLC (CN) | 2016-09-21 | — | — | EP | disclosed |