SCHEMBL47590

SCHEMBL47590

CC(C)(C)c1cc(C(N)=O)cc(C(C)(C)C)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
RECQL P46063 1/20 0.55
CA2 P00918 3/20 0.54
CA1 P00915 2/20 0.54
SMN1; SMN2 Q16637 3/20 0.52
ALDH1A1 P00352 2/20 0.52
POLB P06746 1/20 0.52
TYR P14679 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ALOX5 P09917 2/20 0.51
PTGS1 P23219 2/20 0.51
PTGS2 P35354 2/20 0.51
GAA P10253 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
GLRA3 O75311 1/20 0.50
GLRB P48167 1/20 0.50
TNFRSF1A P19438 1/20 0.47
EGFR P00533 1/20 0.47
MEN1 O00255 1/20 0.47
GALR3 O60755 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30924511 0.88 CYP1A2 (0.55) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL45856 0.88 LMNA (0.53) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL8960347 0.85 LMNA (0.50) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL20099506 0.84 GABRA1 (0.42) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL10001153 0.83 LMNA (0.55) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL6136796 0.83 LMNA (0.55) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL8495448 0.82 ALOX5 (0.65) LMNARECQLCA2CA1SMN1; SMN2
Hydrazine SCHEMBL9180071 0.81 GLRA3 (0.59) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL28333456 0.80 LMNA (0.49) LMNARECQLCA2CA1SMN1; SMN2
SCHEMBL4448135 0.80 LMNA (0.56) LMNARECQLCA2CA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432054-A Flame-retardant high-low temperature-resistant medium-voltage cable 广东金祥羽电线电缆有限公司 2025-02-14 CN claimed
CN-116814067-A Wide-temperature-range high-damping thermoplastic polyether ester elastomer composition and preparation method thereof 会通新材料(上海)有限公司 2023-09-29 CN claimed
CN-116396250-A Phthalate benzofuranone compound, and preparation method and application thereof 天津利安隆新材料股份有限公司 2023-07-07 CN claimed
CN-104109119-B N '-sweet-smelling formacyls neighbour's pyridine hydrazide derivatives and its preparation method and pharmaceutical composition and purposes 中国医学科学院药物研究所 2018-09-25 CN claimed
EP-1022272-B1 SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS SANKYO CO (JP) 2004-05-26 EP claimed
US-6432993-B1 BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 2002-08-13 US claimed
EP-1022272-A1 SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS Sankyo Company Limited (JP) 2000-07-26 EP claimed
EP-0791004-B1 ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION AMERICAN HOME PROD (US) 1999-09-08 EP claimed
US-5773420-A Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation AMERICAN HOME PRODUCTS CORPORATION (US) 1998-06-30 US claimed
EP-0791004-A1 ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION AMERICAN HOME PRODUCTS CORPORATION (US) 1997-08-27 EP claimed
WO-1996014325-A1 ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION AMERICAN HOME PRODUCTS CORPORATION (US) 1996-05-17 WO claimed
US-5510478-A TREATMENT OF NEUROLOGICAL ILLNESSES RELATED TO CHOLINERGIC DEFICIENCY; ALZHEIMERS'S DISEASE AMERICAN HOME PRODUCTS CORPORATION (US) 1996-04-23 US claimed
EP-0404039-B1 PHARMACEUTICALS CONTAINING DI-TERT.BUTYLHYDROXYPHENYL-DERIVATIVES AND NEW DERIVATIVES Roche Diagnostics GmbH (DE) 1993-01-13 EP claimed
CN-120157988-A Polypropylene composite material and preparation method and application thereof 上海金发科技发展有限公司 2025-06-17 CN disclosed
CN-119899485-A PS/PE alloy composite material and preparation method and application thereof 武汉金发科技有限公司 2025-04-29 CN disclosed
CN-118184892-B Graft copolymer composition, ABS resin, and preparation method and application thereof 金发科技股份有限公司 2025-03-25 CN disclosed
EP-0274351-A1 Substituted 1,3,4-oxathiazol-2-one stabilizers CIBA-GEIGY AG (CH) 1988-07-13 EP disclosed
US-4724246-A Substituted 1,3,4-oxathiazol-2-one stabilizers CIBA-GEIGY CORPORATION (US) 1988-02-09 US disclosed
US-3972927-A Alkylamides of hindered 3,5-dialkyl-4-hydroxybenzoic acids and use as light stabilizers in polyolefins AMERICAN CYANAMID COMPANY (US) 1976-08-03 US disclosed
US-3932324-A NICKEL COMPLEXES WITH 2,2-THIOBIS(ALKYLPHENOL), HYDROXYALKYLAMIDES AMERICAN CYANAMID COMPANY (US) 1976-01-13 US disclosed