SCHEMBL18083580

SCHEMBL18083580

CC[C@H]1CC[C@@H](c2cc(F)c(-c3cc(F)c(F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TLR9 Q9NR96 1/20 0.31
TLR8 Q9NR97 1/20 0.31
TLR7 Q9NYK1 1/20 0.31
TRPV3 Q8NET8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965525 1.00 ALDH1A1 (0.33) ALDH1A1TLR9TLR8TLR7TRPV3
SCHEMBL16488482 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9763946 0.90 TRPV3 (0.34) ALDH1A1TRPV3
SCHEMBL8860603 0.90 TRPV3 (0.34) ALDH1A1TRPV3
SCHEMBL21626052 0.90 ALDH1A1 (0.30) ALDH1A1
SCHEMBL13636638 0.89 ALDH1A1 (0.33) ALDH1A1TLR9TLR8TLR7TRPV3
SCHEMBL15965526 0.88 CYP2C9 (0.40) ALDH1A1
SCHEMBL3152900 0.87 TRPV3 (0.31) TRPV3
SCHEMBL3152908 0.87 TRPV3 (0.31) TRPV3
SCHEMBL6454920 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2703473-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DAINIPPON INK & CHEMICALS (JP) 2016-09-21 EP disclosed