Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 7/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083586 | 0.96 | NPC1 (0.41) | HSD11B1NPC1RAB9AATMRARB | |
| SCHEMBL18083584 | 0.95 | NPC1 (0.40) | HSD11B1NPC1RAB9AATMRARB | |
| SCHEMBL18083599 | 0.92 | MGLL (0.34) | NPC1RAB9AATMMGLLMAPT | |
| SCHEMBL2607155 | 0.88 | MGLL (0.42) | HSD11B1NPC1RAB9AATMTP53 | |
| SCHEMBL18083576 | 0.87 | HSD17B10 (0.34) | NPC1RAB9ATP53SMN1; SMN2HSD17B10 | |
| SCHEMBL18473079 | 0.86 | TRPA1 (0.38) | NPC1RAB9AATMFAAHMGLL | |
| SCHEMBL12620346 | 0.85 | HSD11B1 (0.42) | HSD11B1RARBAKR1C2AKR1C1HRH3 | |
| SCHEMBL12620278 | 0.85 | HSD11B1 (0.42) | HSD11B1RARBAKR1C2AKR1C1HRH3 | |
| SCHEMBL18083582 | 0.84 | P2RX4 (0.32) | HSD11B1NPC1RAB9ATP53POLB | |
| SCHEMBL11916914 | 0.84 | MGLL (0.39) | HSD11B1NPC1RAB9AATMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301983-B1 | PHENOXAZINE POLYMERIC COMPOUND AND LIGHT-EMITTING ELEMENT COMPRISING SAME | SUMITOMO CHEMICAL CO (JP) | 2016-09-21 | — | — | EP | disclosed |