Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20601792 | 0.83 | PTGES (0.52) | PTGESHCRTR1GAALMNASORT1 | |
| SCHEMBL31585802 | 0.83 | PTGES (0.52) | PTGESHCRTR1GAALMNASORT1 | |
| SCHEMBL31585832 | 0.82 | ABL1 (0.53) | PTGESHCRTR1GAALMNAKCNK3 | |
| SCHEMBL17017416 | 0.81 | HCRTR1 (0.80) | HCRTR1 | |
| SCHEMBL30416485 | 0.81 | SORT1 (0.72) | SORT1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26405724 | 0.80 | SORT1 (0.54) | PTGESGAALMNASORT1KCNK3 | |
| SCHEMBL30416204 | 0.80 | DEGS1 (0.60) | PTGESHCRTR1GAALMNAKCNK3 | |
| Hydrochloric Acid SCHEMBL30416671 | 0.80 | SORT1 (0.70) | SORT1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26405742 | 0.79 | PTGES (0.51) | PTGESGAALMNASORT1KCNK3 | |
| SCHEMBL25383706 | 0.78 | PTGS1 (0.61) | PTGESHCRTR1GAALMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271348-B1 | NEW FYN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2019-01-30 | — | — | EP | disclosed |
| US-20180111919-A1 | NEW FYN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2018-04-26 | — | — | US | disclosed |
| WO-2016146220-A1 | NEW FYN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2016-09-22 | — | — | WO | disclosed |
| EP-3070084-A1 | NEW FYN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2016-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111919-A1 | NEW FYN KINASE INHIBITORS | FYN, LCK, LYN | PTGES 860/4885HCRTR1 4038/4885GAA 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.