Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26405724 | 0.89 | SORT1 (0.54) | PTGESPOLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL26405685 | 0.87 | ABL1 (0.54) | PTGESPOLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL26405876 | 0.85 | RAB9A (0.63) | POLBKDM4ESMN1; SMN2KMT2AKCNK3 | |
| SCHEMBL5738920 | 0.81 | PTGES (0.59) | PTGESKDM4ESMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL18083760 | 0.79 | PTGES (0.53) | PTGESKDM4ESMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL31585829 | 0.75 | HCAR3 (0.63) | PTGESKDM4ESMN1; SMN2KMT2AKCNK3 | |
| SCHEMBL5234574 | 0.75 | HCAR3 (0.63) | PTGESKDM4ESMN1; SMN2KMT2AKCNK3 | |
| SCHEMBL26405652 | 0.75 | PTGES (0.57) | PTGESKDM4ESMN1; SMN2KMT2AKCNK3 | |
| SCHEMBL30416204 | 0.75 | DEGS1 (0.60) | PTGESKDM4ESMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL25383706 | 0.74 | PTGS1 (0.61) | PTGESKDM4ESMN1; SMN2KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253367-A1 | NOVEL BENZAZEPINE SPIRO DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |