Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22160238 | 0.90 | FDPS (0.56) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160252 | 0.88 | FDPS (0.54) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18083803 | 0.86 | FDPS (0.50) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL26908625 | 0.83 | FDPS (0.54) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160263 | 0.83 | FDPS (0.57) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160286 | 0.83 | FDPS (0.57) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160278 | 0.83 | FDPS (0.57) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18083862 | 0.82 | FDPS (0.47) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18083848 | 0.82 | FDPS (0.47) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL15087786 | 0.82 | FDPS (0.53) | FDPSALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2863925-B1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-09-14 | — | — | EP | disclosed |