Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.53 |
| ▸ | HPGD | P15428 | 11/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22160263 | 1.00 | FDPS (0.57) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160278 | 1.00 | FDPS (0.57) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL30407414 | 0.92 | FDPS (0.58) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18083803 | 0.92 | FDPS (0.50) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160238 | 0.89 | FDPS (0.56) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18083862 | 0.88 | FDPS (0.47) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18083848 | 0.88 | FDPS (0.47) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160232 | 0.88 | ALDH1A1 (0.67) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160231 | 0.88 | FDPS (0.56) | FDPSALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL22160252 | 0.87 | FDPS (0.54) | FDPSALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207744-A1 | DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA | EXPANSION THERAPEUTICS, INC. | 2020-07-02 | — | — | US | disclosed |
| US-20200207744-A1 | DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA | EXPANSION THERAPEUTICS, INC. | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207744-A1 | DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA | HNRNPH1, HNRNPUL2, HNRNPH3 | FDPS 1677/4885ALDH1A1 4110/4885HPGD 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.