Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083848 | 1.00 | FDPS (0.47) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL18083803 | 0.96 | FDPS (0.50) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL22160286 | 0.88 | FDPS (0.57) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL22160263 | 0.88 | FDPS (0.57) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL22160278 | 0.88 | FDPS (0.57) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL18083802 | 0.82 | FDPS (0.50) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL30407414 | 0.81 | FDPS (0.58) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL18083861 | 0.81 | FDPS (0.42) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL22160238 | 0.78 | FDPS (0.56) | FDPSALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL22160231 | 0.77 | FDPS (0.56) | FDPSALDH1A1HPGDMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2863925-B1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-09-14 | — | — | EP | disclosed |