Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29609574 | 1.00 | MIF (0.54) | MIFHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8676885 | 0.89 | MIF (0.44) | MIFHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL483888 | 0.84 | MIF (0.67) | MIFKMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL11430455 | 0.82 | HTR3E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29116581 | 0.81 | TRPV1 (0.43) | MIFHTR3EHTR3BHTR3AHTR3D | |
| Bitoscanate SCHEMBL11598436 | 0.79 | MIF (0.68) | MIFKMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL30102029 | 0.79 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7870699 | 0.79 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7870702 | 0.79 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL58110 | 0.78 | TDP1 (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080660-A | Thiosemicarbazide menthyl formate compound, preparation method and application thereof | 南京林业大学 | 2024-12-06 | — | — | CN | claimed |
| CN-117843276-B | Multi-component composite steel slag grinding-aid excitant and preparation method thereof | 华新水泥股份有限公司 | 2024-11-26 | — | — | CN | claimed |
| WO-2024177606-A1 | QUINAZOLINONE DERIVATIVE COMPOUNDS SHOWING ANTI-CANCER ACTIVITY AND THE SYNTHESIS METHODS OF THESE COMPOUNDS | BILECIK SEYH EDEBALI UNIVERSITESI (TR) | 2024-08-29 | — | — | WO | claimed |
| CN-114751868-B | Diaryl substituted triazole acetic acid compound, and preparation method and application thereof | 山东理工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117843276-A | Multi-component composite steel slag grinding-aid excitant and preparation method thereof | 华新水泥股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117247409-A | 3-thio/seleno-phosphorylated imidazole derivative and synthetic method and application thereof | 曲阜师范大学 | 2023-12-19 | — | — | CN | claimed |
| CN-116916755-A | Materials and methods for extending the shelf life of food products | JP实验室公司 | 2023-10-20 | — | — | CN | claimed |
| CN-114751868-A | Diaryl-substituted triazole acetic acid compound and preparation method and application thereof | 山东理工大学 | 2022-07-15 | — | — | CN | claimed |
| CN-109705146-B | 2-aminobenzo [4, 5] thieno [3, 2-d ] thiazole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-109705146-A | 2- amino benzo [4,5] thieno [3,2-d] thiazole, derivative and its synthetic method | 湘潭大学 | 2019-05-03 | — | — | CN | claimed |
| CN-103992265-A | Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof | UNIV XI AN JIAOTONG | 2014-08-20 | — | — | CN | claimed |
| CN-103444759-A | Isorhodanate and matrine mixture and its application | WUHAN LELIJI BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | claimed |
| CN-101731259-A | Application of isothiocyanate in preparation of termite preventing and controlling agent | WUHAN ROCK BIOTECH CO LTD | 2010-06-16 | — | — | CN | claimed |
| CN-101731258-A | Composition of aromatic isothiocyanate and allyl isothiocyanate and application thereof | WUHAN ROCK BIOTECH CO LTD | 2010-06-16 | — | — | CN | claimed |
| WO-2010065329-A2 | NANOPARTICLES FOR CANCER TREATMENT | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-06-10 | — | — | WO | claimed |
| CN-101356165-A | Process for preparing gemcitabine and related intermediates | CHEMAGIS LTD (IL) | 2009-01-28 | — | — | CN | claimed |
| US-20070249823-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-10-25 | — | — | US | claimed |
| WO-2007070804-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-06-21 | — | — | WO | claimed |
| US-20060241178-A1 | Compositions and methods for treating lung cancer | IMMUNEGUARD LLC (US) | 2006-10-26 | — | — | US | claimed |
| WO-2004060365-A1 | COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER | AMERICAN HEALTH FOUNDATION (US) | 2004-07-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249823-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | DPYD, PARP1, PARP2 | MIF 4268/4885HTR3E 2057/4885HTR3B 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.