Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172448 | 1.00 | KDM4E (0.37) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL20179411 | 0.87 | NFE2L2 (0.48) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL803253 | 0.82 | PTGS2 (0.38) | PTGS2PTGS1HPGD | |
| SCHEMBL15681344 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TP53TSHRPTGS2PTGS1 | |
| SCHEMBL10301567 | 0.80 | CYP2A6 (0.43) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL17016778 | 0.79 | NFE2L2 (0.30) | NFE2L2 | |
| SCHEMBL18219772 | 0.79 | KCNA3 (0.32) | NFE2L2 | |
| SCHEMBL13111462 | 0.79 | NFE2L2 (0.44) | LMNATP53CYP3A4TSHRCNR2 | |
| SCHEMBL18088066 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL19845817 | 0.78 | CHKA (0.35) | KDM4EALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183573-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
| US-9944416-B2 | Filling device and use thereof for dispensing a fluid | MERCK PATENT GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-9737854-B2 | Process for the purification of a liquid-crystal mixture | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| US-20160325231-A1 | PROCESS FOR THE PURIFICATION OF A LIQUID-CRYSTAL MIXTURE | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-20160272346-A1 | FILLING DEVICE AND USE THEREOF FOR DISPENSING A FLUID | MERCK PATENT GMBH (DE) | 2016-09-22 | — | — | US | disclosed |