SCHEMBL1808770

SCHEMBL1808770

O=Cc1c(Cl)c(Cl)c(C=O)c(Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 1/20 0.33
PADI4 Q9UM07 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4658299 0.96 ALDH1A1 (0.43) MEN1ALDH1A1KMT2ATDP1HSD17B10
SCHEMBL1811779 0.93 ALDH1A1 (0.41) MEN1ALDH1A1KMT2ATDP1HSD17B10
SCHEMBL21643711 0.92 MEN1 (0.45) MEN1ALDH1A1KMT2ATDP1HSD17B10
SCHEMBL13064760 0.88 ALDH1A1 (0.43) MEN1ALDH1A1KMT2ATDP1HSD17B10
SCHEMBL11527300 0.84 MEN1 (0.36) MEN1ALDH1A1KMT2ATDP1
SCHEMBL1806236 0.82 MEN1 (0.35) MEN1ALDH1A1KMT2ATDP1PADI4
SCHEMBL10490629 0.80 MEN1 (0.33) MEN1ALDH1A1KMT2ATDP1
SCHEMBL1811988 0.79 MEN1 (0.38) MEN1ALDH1A1KMT2ATDP1
SCHEMBL10611664 0.78 MEN1 (0.32) MEN1ALDH1A1KMT2ATDP1
SCHEMBL5709250 0.78 MEN1 (0.55) MEN1ALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655868-A Solid phase microextraction adsorbent of bis-p-chlorophenyl trichloroethane 北京联合大学 2023-08-29 CN claimed
CN-116655868-B Solid phase microextraction adsorbent of bis-p-chlorophenyl trichloroethane 北京联合大学 2025-09-09 CN disclosed
CN-116655868-A Solid phase microextraction adsorbent of bis-p-chlorophenyl trichloroethane 北京联合大学 2023-08-29 CN disclosed
CN-116655868-A Solid phase microextraction adsorbent of bis-p-chlorophenyl trichloroethane 北京联合大学 2023-08-29 CN disclosed
EP-1915331-B1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO KK (JP) 2013-07-10 EP disclosed
CN-102030624-B Preparation method of 2,3,5,6-tetrachloro-terephthalaldehyde SHANGHAI HETENG FINE CHEMICAL CO LTD 2013-06-05 CN disclosed
CN-102030624-B Preparation method of 2,3,5,6-tetrachloro-terephthalaldehyde SHANGHAI HETENG FINE CHEMICAL CO LTD 2013-06-05 CN disclosed
CN-102030624-B Preparation method of 2,3,5,6-tetrachloro-terephthalaldehyde SHANGHAI HETENG FINE CHEMICAL CO LTD 2013-06-05 CN disclosed
US-7939695-B2 Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO K.K. (JP) 2011-05-10 US disclosed
CN-101193843-B Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO KK 2011-05-04 CN disclosed
CN-102030624-A Preparation method of 2,3,5,6-tetrachloro-terephthalaldehyde SHANGHAI HETENG FINE CHEMICAL CO LTD 2011-04-27 CN disclosed
CN-102030624-A Preparation method of 2,3,5,6-tetrachloro-terephthalaldehyde SHANGHAI HETENG FINE CHEMICAL CO LTD 2011-04-27 CN disclosed
CN-102030624-A Preparation method of 2,3,5,6-tetrachloro-terephthalaldehyde SHANGHAI HETENG FINE CHEMICAL CO LTD 2011-04-27 CN disclosed
US-20100145106-A1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2010-06-10 US disclosed
CN-101193843-A Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO KK (JP) 2008-06-04 CN disclosed
US-4883844-A FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE THE DOW CHEMICAL COMPANY (US) 1989-11-28 US disclosed
US-4205193-A CATALYST FROM ALUMINUM AND TITANIUM COMPOUND, ORGANOOXYGEN COMPOUND AND ORGANOSULFUR CONTAINING COMPOUND MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145106-A1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL NPM1, MED1, KPNA2 MEN1 110/4885ALDH1A1 1151/4885KMT2A 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.