SCHEMBL4658299

SCHEMBL4658299

O=Cc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
UCHL1 P09936 1/20 0.33
UCHL3 P15374 1/20 0.33
ECE1 P42892 1/20 0.33
MUS81 Q96NY9 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.32
PADI4 Q9UM07 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1811779 0.96 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ATDP1UCHL1
SCHEMBL1808770 0.96 MEN1 (0.45) ALDH1A1MEN1KMT2ATDP1HSD17B10
SCHEMBL13064760 0.92 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ATDP1UCHL1
SCHEMBL21643711 0.88 MEN1 (0.45) ALDH1A1MEN1KMT2ATDP1HSD17B10
SCHEMBL10490629 0.83 MEN1 (0.33) ALDH1A1MEN1KMT2ATDP1
SCHEMBL11527300 0.81 MEN1 (0.36) ALDH1A1MEN1KMT2ATDP1
SCHEMBL1806236 0.78 MEN1 (0.35) ALDH1A1MEN1KMT2ATDP1PADI4
SCHEMBL11523379 0.78 MEN1 (0.35) ALDH1A1MEN1KMT2ATDP1
SCHEMBL3972601 0.78 TSHR (0.47) ALDH1A1MEN1KMT2ATDP1TSHR
SCHEMBL1817102 0.76 MEN1 (0.33) ALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825566-B Hexachlorobenzene hapten, artificial antigen and antibody as well as preparation methods and application thereof 北京勤邦科技股份有限公司 2024-01-12 CN claimed
CN-111735952-B Test strip and method for detecting hexachlorobenzene 北京勤邦科技股份有限公司 2023-07-11 CN claimed
CN-111825566-A Hexachlorobenzene hapten, artificial antigen and antibody, and preparation method and application thereof 北京勤邦生物技术有限公司 2020-10-27 CN claimed
CN-111735952-A Test strip and method for detecting hexachlorobenzene 北京勤邦生物技术有限公司 2020-10-02 CN claimed
US-10322104-B2 Disulfur bridge linkers for conjugation of a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-06-18 US claimed
EP-1306380-B1 NOVEL EXPANDED PORPHYRINS AND PROCESS FOR THE SYNTHESIS THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2008-12-17 EP claimed
US-6822092-B2 LARGER CYCLIC NITROGEN-NETWORK, RED-SHIFTED ABSORPTION BANDS, MORE FLEXIBLE CONFORMATION OF THE MACROCYCLES, AND COORDINATION ABILITY OF MORE THAN TWO METAL IONS JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2004-11-23 US claimed
US-20030162963-A1 Novel expanded porphyrins and process for the synthesis thereof JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2003-08-28 US claimed
EP-1306380-A1 NOVEL EXPANDED PORPHYRINS AND PROCESS FOR THE SYNTHESIS THEREOF Japan Science and Technology Corporation (JP) 2003-05-02 EP claimed
CN-117603088-A Aromatic aldehyde Schiff base based on amino acid ethyl ester and application thereof in asymmetric alkylation 广东工业大学 2024-02-27 CN disclosed
CN-111825566-B Hexachlorobenzene hapten, artificial antigen and antibody as well as preparation methods and application thereof 北京勤邦科技股份有限公司 2024-01-12 CN disclosed
CN-111735952-B Test strip and method for detecting hexachlorobenzene 北京勤邦科技股份有限公司 2023-07-11 CN disclosed
WO-2022070992-A1 METHOD FOR PRODUCING FLUORINATED AROMATIC ALDEHYDE 東レ株式会社 2022-04-07 WO disclosed
CN-111825566-A Hexachlorobenzene hapten, artificial antigen and antibody, and preparation method and application thereof 北京勤邦生物技术有限公司 2020-10-27 CN disclosed
US-4609756-A Process for the preparation of optionally substituted cinnamic acid in the presence of a catalyst BAYER AKTIENGESELLSCHAFT (DE) 1986-09-02 US disclosed
EP-0178524-A1 Process for the preparation of possibly substituted cinnamic acid in the presence of a catalyst BAYER AG (DE) 1986-04-23 EP disclosed
US-4205193-A CATALYST FROM ALUMINUM AND TITANIUM COMPOUND, ORGANOOXYGEN COMPOUND AND ORGANOSULFUR CONTAINING COMPOUND MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1980-05-27 US disclosed
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed
US-3968159-A Process for preparing azomethines MONSANTO COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10322104-B2 Disulfur bridge linkers for conjugation of a cell-binding molecule CD74, CD2, EPCAM ALDH1A1 900/4885MEN1 1221/4885KMT2A 2757/4885
US-20030162963-A1 Novel expanded porphyrins and process for the synthesis thereof AAAS, PAM, AHR ALDH1A1 3008/4885MEN1 952/4885KMT2A 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.