Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872496 | 0.90 | PTGER2 (0.45) | THRBPTGER2PTGER4PTGER3TLR4 | |
| SCHEMBL11417780 | 0.84 | PTGER2 (0.43) | THRBPTGER2PTGER4PTGER3TLR4 | |
| SCHEMBL2480706 | 0.81 | THRB (0.40) | THRBTLR4ALDH1A1NPSR1KMT2A | |
| SCHEMBL2479884 | 0.81 | THRB (0.40) | THRBTLR4ALDH1A1NPSR1KMT2A | |
| SCHEMBL11800245 | 0.80 | THRB (0.38) | THRB | |
| SCHEMBL28670909 | 0.77 | PTGER2 (0.44) | PTGER2PTGER4PTGER3TLR4HTT | |
| SCHEMBL25893275 | 0.74 | TSHR (0.42) | THRBPTGER2PTGER4PTGER3HTT | |
| SCHEMBL25893304 | 0.74 | TSHR (0.42) | THRBPTGER2PTGER4PTGER3HTT | |
| SCHEMBL9623743 | 0.74 | PTGER2 (0.49) | PTGER2PTGER4PTGER3HTTTSHR | |
| SCHEMBL5872360 | 0.73 | PTGER2 (0.45) | PTGER2PTGER4PTGER3TLR4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901129-A1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | L'OREAL (FR) | 2021-10-27 | — | — | EP | disclosed |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | L'OREAL (FR) | 2021-05-04 | — | — | US | disclosed |
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | L'OREAL (FR) | 2020-05-19 | — | — | US | disclosed |
| US-20200131108-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID | L'OREAL (FR) | 2020-04-30 | — | — | US | disclosed |
| US-20180057440-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | L'OREAL (FR) | 2018-03-01 | — | — | US | disclosed |
| US-20180057440-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | L'OREAL (FR) | 2018-03-01 | — | — | US | disclosed |
| WO-2016146588-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | L'OREAL (FR) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | HSD17B12, FASN, AKR1C3 | THRB 3677/4885PTGER2 1231/4885PTGER4 1679/4885 |
| US-20180057440-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | HSD17B12, FASN, AKR1C3 | THRB 3677/4885PTGER2 1231/4885PTGER4 1679/4885 |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | CYP8B1, HAAO, HSD17B12 | THRB 4340/4885PTGER2 1233/4885PTGER4 1606/4885 |
| US-20200131108-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID | CYP8B1, HAAO, HSD17B12 | THRB 4340/4885PTGER2 1233/4885PTGER4 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.