Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18089428 | 0.87 | ELANE (0.40) | ELANEAAK1MEN1HTTKMT2A | |
| SCHEMBL18089676 | 0.82 | ELANE (0.33) | ELANECA2 | |
| SCHEMBL17410803 | 0.81 | TSHR (0.40) | ELANEAAK1MEN1HTTKMT2A | |
| SCHEMBL17410802 | 0.79 | ELANE (0.40) | ELANEMEN1HTTKMT2ACA2 | |
| SCHEMBL18857950 | 0.77 | ELANE (0.41) | ELANEAAK1MEN1HTTKMT2A | |
| SCHEMBL31006018 | 0.77 | ELANE (0.41) | ELANEAAK1MEN1HTTKMT2A | |
| SCHEMBL23414048 | 0.75 | ELANE (0.39) | ELANECA2 | |
| SCHEMBL18675818 | 0.75 | MTNR1A (0.39) | ELANEMEN1HTTKMT2ACA2 | |
| SCHEMBL18089675 | 0.74 | AAK1 (0.31) | AAK1 | |
| SCHEMBL29570260 | 0.72 | KMT2A (0.35) | PDE4DMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016149393-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2016-09-22 | — | — | WO | disclosed |