Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15887137 | 0.84 | POLB (0.39) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL17930116 | 0.83 | HPGD (0.41) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL12660032 | 0.83 | HPGD (0.41) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL13623807 | 0.82 | SMN1; SMN2 (0.42) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL26031804 | 0.80 | ALDH1A1 (0.39) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL17486903 | 0.78 | MGLL (0.51) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL12284024 | 0.78 | MGLL (0.51) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL18090280 | 0.77 | POLB (0.35) | POLBHSD17B10CYP3A4CYP2C19TSHR | |
| SCHEMBL18090281 | 0.77 | MGLL (0.34) | POLBHSD17B10CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL18090275 | 0.77 | MGLL (0.34) | POLBHSD17B10CYP2C19TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160271267-A1 | ALKYNYL MULTI-ARM POLYETHYLENE GLYCOL DERIVATIVE | JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271267-A1 | ALKYNYL MULTI-ARM POLYETHYLENE GLYCOL DERIVATIVE | F12, IGLV6-57, F11 | POLB 1448/4885HSD17B10 419/4885CYP3A4 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.