SCHEMBL18090490

SCHEMBL18090490

Brc1cc(N(c2ccccc2)c2ccccc2)cc(N(c2ccccc2)c2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 1/20 0.40
MGLL Q99685 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAOA P21397 1/20 0.36
CRHBP P24387 2/20 0.34
CRHR2 Q13324 2/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
HDAC8 Q9BY41 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18090368 1.00 ALDH1A1 (0.40) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL18090476 0.98 ALDH1A1 (0.43) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL17740596 0.93 ALDH1A1 (0.38) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL17878505 0.93 ALDH1A1 (0.42) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL19429273 0.91 ALDH1A1 (0.41) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL18090345 0.91 ALDH1A1 (0.41) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL18090457 0.91 ALDH1A1 (0.41) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL31602212 0.89 ALDH1A1 (0.45) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL12061256 0.89 ALDH1A1 (0.48) ALDH1A1MAPK1MGLLL3MBTL1KDM4E
SCHEMBL18090501 0.89 ALDH1A1 (0.48) ALDH1A1MAPK1MGLLL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180072695-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-03-15 US disclosed
WO-2016148425-A2 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC APPARATUS FOR SAME 덕산네오룩스 주식회사 2016-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072695-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 ALDH1A1 493/4885MAPK1 108/4885MGLL 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.