Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092007 | 0.90 | TP53 (0.31) | TP53GAA | |
| SCHEMBL18092064 | 0.87 | GABRA5 (0.30) | TP53GAA | |
| SCHEMBL18091990 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL18092002 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL18091962 | 0.86 | TP53 (0.30) | TP53GAA | |
| SCHEMBL18092013 | 0.86 | CHRM4 (0.31) | — | |
| SCHEMBL18091988 | 0.86 | — | — | |
| SCHEMBL18092078 | 0.85 | — | — | |
| SCHEMBL18092069 | 0.85 | — | — | |
| SCHEMBL18092052 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427459-B1 | ISOXAZOLE-THIAZOLE DERIVATIVES AS GABA A RECEPTOR INVERSE AGONISTS FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS | HOFFMANN LA ROCHE (CH) | 2016-09-28 | — | — | EP | claimed |