Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4858348 | 0.99 | DRD2 (0.48) | DRD2LMNAGAADRD3HRH3 | |
| Hydrochloric Acid SCHEMBL4855979 | 0.93 | DRD2 (0.50) | DRD2LMNAGAADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL4857842 | 0.85 | SIGMAR1 (0.40) | DRD2LMNAGAADRD3 | |
| SCHEMBL4252633 | 0.84 | HTR7 (0.43) | DRD2LMNAGAADRD3HTR7 | |
| SCHEMBL13806276 | 0.83 | DRD2 (0.52) | DRD2LMNAGAADRD3HRH3 | |
| SCHEMBL13806157 | 0.83 | DRD2 (0.39) | DRD2LMNAGAADRD3 | |
| Hydrochloric Acid SCHEMBL4852492 | 0.83 | HTR7 (0.42) | DRD2LMNAGAADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL4850131 | 0.83 | DRD2 (0.43) | DRD2LMNAGAADRD3HTR7 | |
| Hydrochloric Acid SCHEMBL4253605 | 0.83 | DRD2 (0.38) | DRD2LMNAGAADRD3 | |
| Hydrochloric Acid SCHEMBL4260192 | 0.83 | DRD2 (0.51) | DRD2LMNAGAADRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698620-B1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | EISAI R&D MAN CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |