Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377656 | 1.00 | ALDH1A1 (0.39) | ALDH1A1BLMKMT2AMEN1POLB | |
| SCHEMBL15307694 | 0.91 | ALDH1A1 (0.38) | ALDH1A1BLMKMT2AMEN1POLB | |
| SCHEMBL14377658 | 0.88 | RIPK1 (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2RIPK1 | |
| SCHEMBL17837283 | 0.85 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL14377695 | 0.84 | SMN1; SMN2 (0.37) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL21133771 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL14376956 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL14377664 | 0.83 | ALDH1A1 (0.43) | ALDH1A1BLMKMT2AMEN1POLB | |
| SCHEMBL18093599 | 0.83 | ALDH1A1 (0.43) | ALDH1A1BLMKMT2AMEN1POLB | |
| SCHEMBL17858904 | 0.83 | NPC1L1 (0.38) | AVPR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274342-B1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | CALIFORNIA INST OF TECHN (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20190055182-A1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-02-21 | — | — | US | disclosed |
| US-10106479-B2 | Asymmetric catalytic decarboxylative alkyl alkylation using low catalyst concentrations and a robust precatalyst | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-10-23 | — | — | US | disclosed |
| US-20160280623-A1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280623-A1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | IDH3B, IDH3A, CYP51A1 | ALDH1A1 221/4885BLM 865/4885KMT2A 271/4885 |
| US-10106479-B2 | Asymmetric catalytic decarboxylative alkyl alkylation using low catalyst concentrations and a robust precatalyst | IDH3B, IDH3A, CYP51A1 | ALDH1A1 221/4885BLM 865/4885KMT2A 271/4885 |
| US-20190055182-A1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | IDH3B, IDH3A, CYP51A1 | ALDH1A1 221/4885BLM 865/4885KMT2A 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.