SCHEMBL18094243

SCHEMBL18094243

CCO[Si]1(OCC)CCCC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 3/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
OPRM1 P35372 7/20 0.32
OPRD1 P41143 4/20 0.31
OPRK1 P41145 4/20 0.31
SLC6A4 P31645 3/20 0.31
OPRL1 P41146 2/20 0.31
SLC22A1 O15245 1/20 0.31
ADRA1A P35348 1/20 0.31
KCNH2 Q12809 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107820 0.83 OPRM1 (0.33) OPRM1OPRK1SLC6A4OPRL1SLC6A2
SCHEMBL6766076 0.81 SMN1; SMN2 (0.36) SMN1; SMN2NPSR1MEN1CYP1A2CYP3A4
SCHEMBL28453987 0.81 SMN1; SMN2 (0.31) SMN1; SMN2OPRM1
SCHEMBL28887399 0.78 ELANE (0.33) OPRM1OPRD1OPRK1OPRL1
SCHEMBL29061957 0.78 DPP4 (0.34) OPRM1OPRD1OPRK1SLC6A4OPRL1
SCHEMBL7698928 0.76 SMN1; SMN2 (0.33) SMN1; SMN2GAAOPRM1OPRD1OPRK1
SCHEMBL6905831 0.75 SMN1; SMN2 (0.32) SMN1; SMN2OPRM1OPRD1OPRK1SLC6A4
SCHEMBL182247 0.74 OPRM1 (0.35) OPRM1OPRK1SLC6A4OPRL1SLC6A2
Ammonia Solution, Strong SCHEMBL7597471 0.72 OPRM1 (0.34) OPRM1OPRK1SLC6A4OPRL1SLC6A2
SCHEMBL3365469 0.72 OPRM1 (0.34) OPRM1OPRK1SLC6A4OPRL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480411-A High-yield low-cost phenyl silicone oil synthesis process 湖北双键精细化工有限公司 2021-03-12 CN claimed
CN-111218004-B Polyoxysilane, preparation method thereof, glass protection composition and application thereof 比亚迪股份有限公司 2021-06-18 CN disclosed
CN-112480411-A High-yield low-cost phenyl silicone oil synthesis process 湖北双键精细化工有限公司 2021-03-12 CN disclosed
CN-109679499-B Organic silicon release emulsion with excellent anchoring performance and preparation method thereof 中山市聚力有机硅技术有限公司 2021-01-15 CN disclosed
CN-109852203-B Silicon-coatable anti-static emulsion with good stability and preparation method thereof 中山市聚力有机硅技术有限公司 2020-11-13 CN disclosed
CN-109694648-B Organic fluorine-silicon release emulsion with good stability and preparation method thereof 中山市聚力有机硅技术有限公司 2020-11-13 CN disclosed
CN-109666402-B Antistatic release emulsion with good stability and preparation method thereof 中山市聚力有机硅技术有限公司 2020-11-13 CN disclosed
CN-111218004-A Polyoxysilane, preparation method thereof, glass protection composition and application thereof 比亚迪股份有限公司 2020-06-02 CN disclosed
US-9994711-B2 Condensation-curable silicone composition and a semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-12 US disclosed
US-20160280959-A1 CONDENSATION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-29 US disclosed