SCHEMBL182247

SCHEMBL182247

C[Si]1(C)CCCC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.35
OPRK1 P41145 1/20 0.35
OPRL1 P41146 1/20 0.35
ALDH1A1 P00352 1/20 0.33
SLC6A4 P31645 3/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
DPP4 P27487 1/20 0.32
AKR1C1 Q04828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3365469 0.98 OPRM1 (0.34) OPRM1OPRK1OPRL1ALDH1A1SLC6A4
Ammonia Solution, Strong SCHEMBL7597471 0.98 OPRM1 (0.34) OPRM1OPRK1OPRL1ALDH1A1SLC6A4
SCHEMBL6471964 0.83
SCHEMBL3263252 0.80 HSD11B1 (0.36) OPRM1OPRK1OPRL1ALDH1A1SLC6A4
SCHEMBL29061957 0.79 DPP4 (0.34) OPRM1OPRK1OPRL1SLC6A4SLC6A2
SCHEMBL6157096 0.78 AKR1C1 (0.36) OPRM1OPRK1OPRL1DPP4AKR1C1
SCHEMBL7107820 0.77 OPRM1 (0.33) OPRM1OPRK1OPRL1SLC6A4SLC6A2
SCHEMBL2352430 0.76 AKR1C1 (0.35) SLC6A4SLC6A2SLC6A3DPP4AKR1C1
SCHEMBL1552116 0.76 OPRM1 (0.36) OPRM1OPRK1OPRL1
SCHEMBL1993502 0.75 OPRM1 (0.31) OPRM1OPRK1OPRL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381232-A1 BONE DERIVED FIBERS AND OXYGENATED WOUND TREATMENTS TETROUS INC (US) 2025-12-18 US claimed
US-12419916-B2 Bone derived fibers and oxygenated wound treatments TETROUS, INC. (US) 2025-09-23 US claimed
US-20250250692-A1 SUSTAINABLE METHODS AND DEVICES FOR FUEL DECONTAMINATION, FUEL PROCESSING, AND CHEMICALS PRODUCTION CAVAZOS SEPULVEDA ADRIAN CESAR (MX) 2025-08-07 US claimed
EP-4253478-B1 EPOXY RESIN COMPOSITION AND TRANSPARENT COMPOSITE MATERIAL COMPRISING SAME, AND LAMINATED BOARD GUANGDONG HINNO TECH CO LTD (CN) 2025-04-30 EP claimed
EP-4520312-A2 THERAPEUTIC GAS INFUSED COSMETIC AND METHODS OF INFUSION Tetrous, Inc. (US) 2025-03-12 EP claimed
CN-118948631-B Oil-in-water cleansing composition 深圳市护家科技有限公司 2025-02-14 CN claimed
US-12179418-B2 Siloxane additive manufacturing composition SPECTROPLAST AG (CH) 2024-12-31 US claimed
EP-3664770-B1 THERAPEUTIC GAS INFUSED COSMETIC AND METHODS OF INFUSION TETROUS INC (US) 2024-12-04 EP claimed
US-20240343942-A1 CURABLE SILOXANE-MODIFIED RESIN COMPOSITIONS WITH SILICONE-OIL ADDITIVES AND USE THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2024-10-17 US claimed
CN-111356432-B Cosmetic product for therapeutic gas infusion and method of infusion 特劳斯公司 2024-05-31 CN claimed
EP-0424260-A1 Cosmetic use of an aqueous dispersion from organopolysiloxanes and from a cross-linked ammonium acrylate/acrylamide copolymer L'OREAL (FR) 1991-04-24 EP claimed
EP-0398573-A2 Devices featuring silicone elastomers AT&T Corp. (US) 1990-11-22 EP claimed
US-4902499-A Hair care compositions containing a rigid silicone polymer THE PROCTER & GAMBLE COMPANY (US) 1990-02-20 US claimed
US-4849172-A Optical sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-18 US claimed
US-4708833-A Method for producing elastomeric optical fiber SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1987-11-24 US claimed
EP-0243116-A2 Optical sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-10-28 EP claimed
EP-0240350-A2 Hair care compositions THE PROCTER & GAMBLE COMPANY (US) 1987-10-07 EP claimed
US-4544692-A Polysiloxane and fluorocarbon coating composition MATERIAL SCIENCES CORPORATION (US) 1985-10-01 US claimed
US-4369268-A RELEASE COATINGS FOR UTENSILS MATERIAL SCIENCES CORPORATION (US) 1983-01-18 US claimed
US-4153747-A Wrap around heat shrinkable closure SIGMAFORM CORPORATION (US) 1979-05-08 US claimed