Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.47 |
| ▸ | PRKCG | P05129 | 3/20 | 0.47 |
| ▸ | PRKCB | P05771 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 3/20 | 0.47 |
| ▸ | PRKCH | P24723 | 3/20 | 0.47 |
| ▸ | PRKCI | P41743 | 3/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | GMNN | O75496 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1819724 | 1.00 | DNM1 (0.53) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL1772881 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL1773674 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL9808836 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL7720158 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL7718400 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL9808821 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL1773357 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL7720123 | 0.89 | PRKD3 (0.54) | DNM1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL29105923 | 0.88 | DNM1 (0.50) | DNM1PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496552-B1 | DIFUNCTIONAL, AMINE-BASED SURFACTANTS, AND THEIR PRECURSORS, PREPARATION, COMPOSITIONS AND USE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-2496552-A1 | DIFUNCTIONAL, AMINE-BASED SURFACTANTS, AND THEIR PRECURSORS, PREPARATION, COMPOSITIONS AND USE | Dow Global Technologies LLC (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011056620-A1 | DIFUNCTIONAL, AMINE-BASED SURFACTANTS, AND THEIR PRECURSORS, PREPARATION, COMPOSITIONS AND USE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110112328-A1 | Difunctional, Amine-Based Surfactants, and Their Precursors, Preparation, Compositions and Use | DOW GLOBAL TECHNOLOGIES LLC | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112328-A1 | Difunctional, Amine-Based Surfactants, and Their Precursors, Preparation, Compositions and Use | C1S, DEGS1, F12 | DNM1 627/4885PRKD3 1987/4885PRKCG 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.