Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805275 | 0.86 | NPC1 (0.48) | LMNAMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL1809286 | 0.79 | IGF1R (0.40) | MAPTNPC1RAB9A | |
| SCHEMBL1809892 | 0.70 | MEN1 (0.45) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15114294 | 0.66 | LMNA (0.57) | LMNAMAPTMEN1ALOX12KMT2A | |
| SCHEMBL26070898 | 0.65 | BTK (0.49) | MAPTBTKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30480284 | 0.63 | LMNA (0.49) | LMNAMAPTMEN1ALOX12KMT2A | |
| SCHEMBL10643589 | 0.62 | LTA4H (0.54) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL1808855 | 0.62 | MAPK1 (0.52) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL123415 | 0.61 | MAPT (0.55) | LMNAMAPTMEN1ALOX12KMT2A | |
| SCHEMBL23544689 | 0.61 | NQO1 (0.54) | LMNAMAPTMEN1ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |