Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957530 | 0.76 | MAPK1 (0.61) | MAPK1PRMT5MEN1KMT2ARAB9A | |
| SCHEMBL18642527 | 0.75 | NR1H2 (0.42) | RAB9AKDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL2272875 | 0.71 | NPC1 (0.63) | MAPK1PRMT5KMT2ARAB9AKDM4E | |
| SCHEMBL5583002 | 0.71 | MAPK1 (0.56) | MAPK1PRMT5MEN1KMT2ACYP11B1 | |
| SCHEMBL511781 | 0.70 | RAB9A (0.58) | MAPK1PRMT5MEN1KMT2ARAB9A | |
| SCHEMBL1808853 | 0.68 | TEK (0.69) | MEN1KMT2ARAB9ACYP19A1 | |
| SCHEMBL1323646 | 0.68 | RAB9A (0.62) | MAPK1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7311175 | 0.68 | MAPK1 (0.65) | MAPK1MEN1KMT2ARAB9AGRM2 | |
| SCHEMBL30150593 | 0.68 | RAB9A (0.62) | MAPK1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4506543 | 0.68 | CYP11B2 (0.68) | MAPK1PRMT5CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |