SCHEMBL18100489

SCHEMBL18100489

Cc1ccc(-c2c3cc(C)oc3c(-c3ccc(C)cc3)c3cc(C)oc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.41
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
CSNK2A1 P68400 1/20 0.38
MAOB P27338 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP1B1 Q16678 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
KDM4E B2RXH2 3/20 0.35
TNKS O95271 1/20 0.35
PARP1 P09874 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
PARP2 Q9UGN5 1/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21385864 0.68 ACHE (0.61) PTGS2ALDH1A1CA9HPGDHSD17B10
SCHEMBL18100512 0.67 ALDH1A1 (0.38) PTGS2ALDH1A1MAPTCYP1A1CYP1A2
SCHEMBL20872257 0.66 HPGD (0.49) PTGS2ALDH1A1MAPTNPC1RAB9A
SCHEMBL11781328 0.65 MAOB (0.42) PTGS2MAOBALDH1A1MAPTNPC1
SCHEMBL15142199 0.64 ALDH1A1 (0.44) MAOBALDH1A1MAPTCYP1A1CYP1A2
SCHEMBL4420514 0.64 ALDH1A1 (0.45) MAOBALDH1A1MAPTCYP1A1CYP1A2
SCHEMBL12052449 0.64 ALDH1A1 (0.41) ALDH1A1CYP1A1CYP1A2CYP1B1KDM4E
SCHEMBL30742831 0.62 ACHE (0.57) PTGS2MAOBALDH1A1NPC1RAB9A
SCHEMBL3477351 0.62 ACHE (0.57) PTGS2MAOBALDH1A1NPC1RAB9A
SCHEMBL1044722 0.62 MEN1 (0.47) CSNK2A2CSNK2BCSNK2A1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9634252-B2 Polymer and solar cell using the same KABUSHIKI KAISHA TOSHIBA (JP) 2017-04-25 US disclosed
US-20160285001-A1 POLYMER AND SOLAR CELL USING THE SAME KABUSHIKI KAISHA TOSHIBA (JP) 2016-09-29 US disclosed