Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594240 | 0.67 | HTT (0.34) | CA2LMNAHTTCA12CA1 | |
| SCHEMBL23748763 | 0.64 | CA2 (0.39) | CA2LMNATDP1ADRB2ADRB1 | |
| SCHEMBL2016585 | 0.62 | CA2 (0.57) | CA2 | |
| SCHEMBL2817756 | 0.61 | GABRA1 (0.55) | HSP90AA1HSP90AB1CA2LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL8148470 | 0.61 | CA2 (0.55) | CA2 | |
| SCHEMBL29718608 | 0.60 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1CA2LMNACYP1A2 | |
| SCHEMBL4983030 | 0.60 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1CA2LMNACYP1A2 | |
| SCHEMBL9797765 | 0.58 | EPHX1 (0.61) | CA2LMNATSHRNFKB1BLM | |
| SCHEMBL27861148 | 0.56 | CA2 (0.39) | CA2KDM4ETSHRHTT | |
| SCHEMBL11290860 | 0.56 | CA2 (0.80) | CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160281075-A1 | USE OF GALERINA MARGINATA GENES AND PROTEINS FOR PEPTIDE PRODUCTION | UNITED STATES DEPARTMENT OF ENERGY | 2016-09-29 | — | — | US | disclosed |