SCHEMBL18101320

SCHEMBL18101320

Brc1cc2c3ccccc3[nH]c2c2sc3ccccc3c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.59
▸ KMT2A Q03164 4/20 0.59
▸ MAPT P10636 3/20 0.59
▸ RAB9A P51151 1/20 0.59
▸ CDK4 P11802 5/20 0.52
▸ CCND1 P24385 5/20 0.52
▸ MAP3K9 P80192 3/20 0.52
▸ MAP3K11 Q16584 3/20 0.52
▸ TNKS O95271 1/20 0.50
▸ TNKS2 Q9H2K2 1/20 0.50
▸ NTRK1 P04629 1/20 0.47
▸ MAP3K10 Q02779 1/20 0.47
▸ AHR P35869 2/20 0.41
▸ PTPN1 P18031 1/20 0.40
▸ GABRP O00591 1/20 0.38
▸ GABRD O14764 1/20 0.38
▸ GABRA1 P14867 1/20 0.38
▸ GABRB1 P18505 1/20 0.38
▸ GABRG2 P18507 1/20 0.38
▸ GABRB3 P28472 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17660906 0.88 MEN1 (0.55) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL20175697 0.82 MEN1 (0.59) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL24593233 0.82 MAPT (0.59) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL20175702 0.81 KIF11 (0.42) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL25681761 0.80 MEN1 (0.56) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL25201976 0.79 MEN1 (0.55) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL15138782 0.76 MEN1 (0.69) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL30887363 0.76 MEN1 (0.69) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL22011388 0.76 MAP3K9 (0.67) MEN1KMT2AMAPTRAB9ACDK4
SCHEMBL29506382 0.76 MEN1 (0.69) MEN1KMT2AMAPTRAB9ACDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266787-B1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2022-07-06 — — EP disclosed
US-20180201621-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-07-19 — — US disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed
WO-2018034444-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2018-02-22 — — WO disclosed
WO-2016153198-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2016-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180201621-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 MEN1 718/4885KMT2A 1263/4885MAPT 2905/4885
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 MEN1 658/4885KMT2A 1257/4885MAPT 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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