SCHEMBL18101369

SCHEMBL18101369

Brc1cc2c3ccccc3n(-c3ccc4ccccc4c3)c2c2c1sc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PMM2 O15305 1/20 0.37
▸ MPI P34949 1/20 0.37
▸ PHOSPHO1 Q8TCT1 1/20 0.37
▸ PTPN1 P18031 3/20 0.34
▸ TP53 P04637 3/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MAPT P10636 3/20 0.31
▸ RXFP1 Q9HBX9 1/20 0.31
▸ PTPRC P08575 1/20 0.31
▸ PTPRF P10586 1/20 0.31
▸ PTPRA P18433 1/20 0.31
▸ PTPRB P23467 1/20 0.31
▸ PTPN6 P29350 1/20 0.31
▸ DUSP3 P51452 1/20 0.31
▸ PTPN12 Q05209 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20175696 0.91 PMM2 (0.37) PMM2MPIPHOSPHO1PTPN1TP53
SCHEMBL18101303 0.87 PTPN1 (0.34) PTPN1TP53HPGDMAPTRXFP1
SCHEMBL18101099 0.87 ATM (0.44) PTPN1TP53MAPTRXFP1PTPRC
SCHEMBL18101368 0.85 PMM2 (0.36) PMM2MPIPHOSPHO1PTPN1RXFP1
SCHEMBL18101367 0.85 PTPN1 (0.37) PTPN1TP53RXFP1PTPRCPTPRF
SCHEMBL17427709 0.84 PMM2 (0.39) PMM2MPIPHOSPHO1TP53HPGD
SCHEMBL20175711 0.84 PMM2 (0.37) PMM2MPIPHOSPHO1PTPN1TP53
SCHEMBL19889568 0.83 PTPN1 (0.35) PTPN1MAPTRXFP1PTPRCPTPRF
SCHEMBL18101421 0.83 PMM2 (0.34) PMM2MPIPHOSPHO1TP53MAPT
SCHEMBL20175731 0.83 PTPN1 (0.36) PTPN1TP53MAPTRXFP1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020085793-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-04-30 — — WO disclosed
US-20180201621-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-07-19 — — US disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed
WO-2016153198-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2016-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180201621-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 PMM2 3201/4885MPI 4055/4885PHOSPHO1 678/4885
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 PMM2 3604/4885MPI 4125/4885PHOSPHO1 809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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