SCHEMBL20175731

SCHEMBL20175731

Brc1cc2c3ccccc3n(-c3cccc(-c4ccccc4)c3)c2c2c1sc1ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 4/20 0.36
▸ MAPT P10636 2/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ ATM Q13315 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ PTPRC P08575 1/20 0.34
▸ PTPRF P10586 1/20 0.34
▸ PTPRA P18433 1/20 0.34
▸ PTPRB P23467 1/20 0.34
▸ PTPN6 P29350 1/20 0.34
▸ DUSP3 P51452 1/20 0.34
▸ PTPN12 Q05209 1/20 0.34
▸ TP53 P04637 1/20 0.33
▸ TNKS O95271 1/20 0.31
▸ TNKS2 Q9H2K2 1/20 0.31
▸ PDE4A P27815 1/20 0.30
▸ PDE4B Q07343 1/20 0.30
▸ PDE4C Q08493 1/20 0.30
▸ PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20175709 0.91 PTPN1 (0.36) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL18101367 0.91 PTPN1 (0.37) PTPN1RXFP1ATMKDM4EL3MBTL1
SCHEMBL18101099 0.91 ATM (0.44) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL20175769 0.89 PTPN1 (0.36) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL18101413 0.86 MAPT (0.32) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL18101402 0.86 MAPT (0.32) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL20175710 0.84 TNKS (0.36) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL18101303 0.84 PTPN1 (0.34) PTPN1MAPTRXFP1ATMKDM4E
SCHEMBL17990901 0.83 MAPT (0.35) MAPTRXFP1ATMKDM4EL3MBTL1
SCHEMBL18101369 0.83 PMM2 (0.37) PTPN1MAPTRXFP1PTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266787-B1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2022-07-06 — — EP disclosed
US-10717744-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-07-21 — — US disclosed
WO-2020085793-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-04-30 — — WO disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141957-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 PTPN1 3017/4885MAPT 3092/4885RXFP1 4286/4885
US-10717744-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OCIAD1, LEF1 PTPN1 3017/4885MAPT 3092/4885RXFP1 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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