Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817092 | 0.82 | EGLN1 (0.43) | EGLN1ATRKDM4EALDH1A1RCE1 | |
| SCHEMBL1809791 | 0.76 | TP53 (0.47) | EGLN1KDM4EGAAHPGDL3MBTL1 | |
| SCHEMBL1810167 | 0.75 | EGLN1 (0.40) | EGLN1LCKKDM4EALDH1A1RCE1 | |
| SCHEMBL31636581 | 0.73 | KDM4E (0.40) | LCKKDM4EALDH1A1GAAHTT | |
| SCHEMBL1809247 | 0.72 | KDM4E (0.47) | EGLN1LCKKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1811979 | 0.72 | HPGD (0.44) | ATRKDM4EALDH1A1RCE1GAA | |
| SCHEMBL1974306 | 0.72 | LCK (0.36) | EGLN1LCKKDM4EALDH1A1HPGD | |
| SCHEMBL7846101 | 0.71 | KDM4E (0.56) | KDM4EALDH1A1RCE1GAAGLA | |
| SCHEMBL23580382 | 0.70 | NR4A2 (0.43) | EGLN1LCKKDM4EALDH1A1GAA | |
| SCHEMBL1816427 | 0.69 | EGLN1 (0.46) | EGLN1KDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |