Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68412 | 0.91 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL5948910 | 0.87 | FOLH1 (0.46) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1515865 | 0.86 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1809809 | 0.86 | CYP4Z1 (0.54) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL6511742 | 0.85 | PAM (0.51) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL2457851 | 0.85 | SLC7A5 (0.47) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1401401 | 0.85 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL3620906 | 0.85 | PAM (0.51) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL2630609 | 0.83 | PPARA (0.51) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL8150062 | 0.83 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2NPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935700-B2 | Morpholine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20070265257-A1 | Morpholine Compound | MITSUBISHI PHARMA CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265257-A1 | Morpholine Compound | CCR3, CCR1, CCR4 | L3MBTL1 1798/4885SMN1; SMN2 932/4885NPC1 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.