Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975540 | 0.91 | NR1I2 (0.53) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL19387708 | 0.85 | ADORA3 (0.54) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL17399522 | 0.85 | ADORA3 (0.54) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL2425661 | 0.84 | TSHR (0.67) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL2425660 | 0.84 | TSHR (0.67) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL15634237 | 0.84 | ALDH1A1 (0.56) | NR1I2PTGS2ALOX5OXER1TSHR | |
| SCHEMBL14166705 | 0.84 | ALDH1A1 (0.56) | NR1I2PTGS2ALOX5OXER1TSHR | |
| SCHEMBL14241681 | 0.84 | ALDH1A1 (0.56) | NR1I2PTGS2ALOX5OXER1TSHR | |
| SCHEMBL32662839 | 0.84 | ALOX5 (0.69) | ALOX5OXER1CNR1CNR2MGLL | |
| SCHEMBL9186992 | 0.84 | ALOX5 (0.64) | NR1I2PGRADORA3PTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10168342-B2 | Lipid probes and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-01 | — | — | US | disclosed |
| WO-2016160544-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20160282369-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-09-29 | — | — | US | disclosed |
| US-20160282369-A1 | LIPID PROBES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-09-29 | — | — | US | disclosed |