SCHEMBL181033

SCHEMBL181033

CCCCCCCCCCCCSC(=S)SC(C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.45
MAPT P10636 2/20 0.41
HSD17B10 Q99714 2/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
THRB P10828 1/20 0.41
CYP2C9 P11712 1/20 0.41
BLM P54132 1/20 0.41
ACHE P22303 3/20 0.39
ACE2 Q9BYF1 1/20 0.39
GPR84 Q9NQS5 6/20 0.38
FFAR1 O14842 2/20 0.38
PPARD Q03181 5/20 0.37
CES2 O00748 1/20 0.37
LCK P06239 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
PPARG P37231 4/20 0.34
PPARA Q07869 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31539134 1.00 EPHX1 (0.45) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL180793 0.93 EPHX1 (0.36) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL28139458 0.83 EPHX1 (0.47) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL4455370 0.81 GPR84 (0.40) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL28792134 0.81 HSD17B10 (0.42) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL19450501 0.80 EPHX1 (0.39) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL3065227 0.80 HSD17B10 (0.41) MAPTHSD17B10GMNNTP53POLB
SCHEMBL28411727 0.79 ACHE (0.40) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL16166726 0.79 ACE2 (0.45) EPHX1MAPTHSD17B10GMNNTP53
SCHEMBL28107250 0.78 GPR84 (0.42) MAPTHSD17B10GMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12359008-B2 Alternating copolymers of selected unsymmetrically substituted stilbenes and maleic anhydride or N-substituted maleimides VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2025-07-15 US claimed
CN-118580442-A Method for preparing self-repairing functional material based on Ugi reaction and dynamic borate ester bond by one-pot method 平顶山神马工程塑料科技发展有限公司 2024-09-03 CN claimed
CN-118436791-A Multifunctional drug carrier with lubricating and active oxygen response effects, drug, preparation method and application thereof 清华大学 2024-08-06 CN claimed
US-11708446-B2 Polymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-25 US claimed
US-20230089076-A1 ALTERNATING COPOLYMERS OF SELECTED UNSYMMETRICALLY SUBSTITUTED STILBENES AND MALEIC ANHYDRIDE OR N-SUBSTITUTED MALEIMIDES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2023-03-23 US claimed
US-11078302-B2 Polymerization methods NORTH CAROLINA STATE UNIVERSITY (US) 2021-08-03 US claimed
US-20210221937-A1 POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-07-22 US claimed
US-11041026-B2 Reactions enabled by thermoresponsive and photoresponsive gels MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-22 US claimed
CN-108935513-B Silver-loaded poly (2-aminoethyl acrylate) antibacterial agent and preparation method thereof 西北工业大学 2021-04-02 CN claimed
US-20190345269-A1 POLYMERIZATION METHODS NORTH CAROLINA STATE UNIVERSITY 2019-11-14 US claimed
WO-2018140977-A1 REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-08-02 WO claimed
EP-3334766-A1 THIOCARBONYLTHIO-FREE RAFT POLYMERS AND THE PROCESS OF MAKING THE SAME Henkel IP & Holding GmbH (DE) 2018-06-20 EP claimed
US-20180155463-A1 THIOCARBONYLTHIO-FREE RAFT POLYMERS AND THE PROCESS OF MAKING THE SAME Henkel IP & Holding GmbH (DE) 2018-06-07 US claimed
WO-2017027557-A1 THIOCARBONYLTHIO-FREE RAFT POLYMERS AND THE PROCESS OF MAKING THE SAME Henkel IP & Holding GmbH (DE) 2017-02-16 WO claimed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US disclosed
US-12617884-B2 Organic fine particle DAIKIN INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
EP-3828225-B1 GEL MATERIAL UNIV HOKKAIDO NAT UNIV CORP (JP) 2026-01-28 EP disclosed
WO-2006037161-A1 SURFACE POLYMERISATION PROCESS AND POLYMER PRODUCT USING RAFT AGENT THE UNIVERSITY OF SYDNEY (AU) 2006-04-13 WO disclosed
EP-1463765-A1 AQUEOUS DISPERSIONS OF POLYMER PARTICLES University of Sydney (AU) 2004-10-06 EP disclosed
WO-2003055919-A1 AQUEOUS DISPERSIONS OF POLYMER PARTICLES UNIVERSITY OF SYDNEY (AU) 2003-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617884-B2 Organic fine particle FUS, AFF1, AFF4 EPHX1 574/4885MAPT 583/4885HSD17B10 3953/4885
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 EPHX1 3116/4885MAPT 4457/4885HSD17B10 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.