Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | AMY2A | P04746 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | PYGB | P11216 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19721647 | 1.00 | SPHK1 (0.34) | SPHK1MGAMGAALGALS8LGALS3 | |
| SCHEMBL19276934 | 1.00 | SPHK1 (0.34) | SPHK1MGAMGAALGALS8LGALS3 | |
| SCHEMBL21233490 | 1.00 | SPHK1 (0.34) | SPHK1MGAMGAALGALS8LGALS3 | |
| SCHEMBL13467759 | 0.88 | SPHK1 (0.36) | SPHK1MGAMGAALGALS8LGALS3 | |
| SCHEMBL19297652 | 0.88 | SPHK1 (0.36) | SPHK1MGAMGAALGALS8LGALS3 | |
| SCHEMBL25995092 | 0.86 | SPHK1 (0.35) | SPHK1MGAMGAALGALS8LGALS3 | |
| SCHEMBL23057091 | 0.85 | AMY2A (0.51) | LGALS8LGALS3AMY2A | |
| SCHEMBL21251555 | 0.85 | AMY2A (0.51) | LGALS8LGALS3AMY2A | |
| SCHEMBL26469994 | 0.85 | AMY2A (0.51) | LGALS8LGALS3AMY2A | |
| SCHEMBL22423210 | 0.85 | LGALS3 (0.37) | SPHK1MGAMGAALGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160279224-A1 | PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160279224-A1 | PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 | STT3A, DDOST, LGALS3BP | SPHK1 970/4885MGAM 172/4885GAA 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.