SCHEMBL25995092

SCHEMBL25995092

COC1C(O)COC(CO)[C@H]1OC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SPHK1 Q9NYA1 1/20 0.35
▸ LGALS8 O00214 2/20 0.31
▸ THRB P10828 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ LGALS3 P17931 1/20 0.31
▸ GAA P10253 2/20 0.31
▸ MGAM O43451 2/20 0.31
▸ OGA O60502 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19297652 0.94 SPHK1 (0.36) SPHK1LGALS8THRBLMNALGALS3
SCHEMBL13467759 0.94 SPHK1 (0.36) SPHK1LGALS8THRBLMNALGALS3
SCHEMBL19276934 0.86 SPHK1 (0.34) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL21233490 0.86 SPHK1 (0.34) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL19721647 0.86 SPHK1 (0.34) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL23603158 0.86 LGALS3 (0.37) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL23603330 0.86 LGALS3 (0.37) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL22423210 0.86 LGALS3 (0.37) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL18104016 0.86 SPHK1 (0.34) SPHK1LGALS8LGALS3GAAMGAM
SCHEMBL8719944 0.86 LGALS3 (0.37) SPHK1LGALS8LGALS3GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235076-A1 HUMANIZED ANTIBODIES AGAINST LEWIS Y PENTIXAPHARM AG (DE) 2023-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235076-A1 HUMANIZED ANTIBODIES AGAINST LEWIS Y FCGR2A, FCGR3B, CD47 SPHK1 3311/4885LGALS8 62/4885THRB 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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