Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 4/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672185 | 0.89 | TLR8 (0.40) | S1PR1S1PR3TLR8KAT8ESR1 | |
| SCHEMBL181328 | 0.89 | TLR8 (0.40) | S1PR1S1PR3TLR8KAT8ESR1 | |
| SCHEMBL181327 | 0.89 | TLR8 (0.40) | S1PR1S1PR3TLR8KAT8ESR1 | |
| SCHEMBL14786518 | 0.89 | TLR8 (0.40) | S1PR1S1PR3TLR8KAT8ESR1 | |
| SCHEMBL14786501 | 0.88 | TLR8 (0.39) | S1PR1S1PR3TLR8THRBESR1 | |
| SCHEMBL14786454 | 0.86 | SIGMAR1 (0.40) | TLR8 | |
| SCHEMBL9791110 | 0.85 | CDK1 (0.51) | CDK1KAT8PPARATHRBLPL | |
| SCHEMBL19506649 | 0.84 | TLR8 (0.36) | S1PR1S1PR3TLR8ESR1ADRA2A | |
| SCHEMBL14786477 | 0.83 | GPR3 (0.37) | TLR8LPLLIPGHTR2A | |
| SCHEMBL16672062 | 0.81 | TLR8 (0.41) | S1PR1S1PR3TLR8KAT8ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796727-B2 | Field effect transistor | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-24 | — | — | US | disclosed |
| US-9796727-B2 | Field effect transistor | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-24 | — | — | US | disclosed |
| EP-2402348-B1 | FIELD EFFECT TRANSISTOR | NIPPON KAYAKU KK (JP) | 2017-04-12 | — | — | EP | disclosed |
| US-20150329538-A1 | AMIDES AS PIM INHIBITORS | AMGEN INC. (US) | 2015-11-19 | — | — | US | disclosed |
| EP-2402348-A1 | FIELD EFFECT TRANSISTOR | Hiroshima University (JP) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010098372-A1 | FIELD EFFECT TRANSISTOR | 国立大学法人広島大学 (JP) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329538-A1 | AMIDES AS PIM INHIBITORS | PIM1, PIM3, PIM2 | CDK1 404/4885S1PR1 3573/4885S1PR3 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.