Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TST | Q16762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181328 | 1.00 | TLR8 (0.40) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL181327 | 1.00 | TLR8 (0.40) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL14786518 | 1.00 | TLR8 (0.40) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL14786501 | 0.99 | TLR8 (0.39) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL14786454 | 0.96 | SIGMAR1 (0.40) | TLR8 | |
| SCHEMBL19506649 | 0.94 | TLR8 (0.36) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL14786477 | 0.93 | GPR3 (0.37) | TLR8HTR2A | |
| SCHEMBL16672062 | 0.91 | TLR8 (0.41) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL181044 | 0.89 | CDK1 (0.42) | TLR8ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL17086837 | 0.87 | ASIC3 (0.43) | TLR8HSD17B10HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018630-B2 | Heterocyclic dinaphtho thieno thiophene (DNTT) compounds for use as organic semiconductor thin films in field effect transistors and related methods | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-04-28 | — | — | US | disclosed |