SCHEMBL18105695

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19920054	0.89	TRPM8 (0.37)	SMN1; SMN2KDM4ETRPM8NPC1RAB9A
	SCHEMBL18105689	0.87	TRPM8 (0.49)	ALDH1A1KDM4ETRPM8NPC1RAB9A
	SCHEMBL18105748	0.84	CYP2C19 (0.55)	SMN1; SMN2ALDH1A1CYP2C19TRPM8NPC1
	SCHEMBL18105910	0.84	SMN1; SMN2 (0.48)	SMN1; SMN2ALDH1A1KDM4ECYP2C19NPC1
	SCHEMBL18105747	0.83	ALDH1A1 (0.52)	SMN1; SMN2ALDH1A1CYP2C19NPC1RAB9A
	SCHEMBL4889806	0.82	TRPM8 (0.57)	SMN1; SMN2ALDH1A1KDM4ETRPM8HPGD
	SCHEMBL18105779	0.81	KDM4E (0.55)	SMN1; SMN2ALDH1A1KDM4ECYP2C19HSD17B10
	SCHEMBL18105713	0.79	TRPM8 (0.49)	SMN1; SMN2ALDH1A1TRPM8MAPTMEN1
	SCHEMBL18105704	0.78	GAA (0.53)	ALDH1A1TRPM8NPC1RAB9AMEN1
	SCHEMBL18105700	0.76	TRPM8 (0.47)	SMN1; SMN2ALDH1A1KDM4ECYP2C19TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.