Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812754 | 0.85 | LIMK1 (0.38) | EGLN1LIMK1CLK1ALDH1A1KDM4E | |
| SCHEMBL1810830 | 0.76 | EGLN1 (0.46) | EGLN1LIMK1ALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL1810773 | 0.73 | EGLN1 (0.71) | EGLN1 | |
| SCHEMBL1819983 | 0.71 | EGLN1 (0.54) | EGLN1 | |
| SCHEMBL1809954 | 0.71 | EGLN1 (0.54) | EGLN1 | |
| SCHEMBL1807792 | 0.71 | EGLN1 (0.54) | EGLN1 | |
| SCHEMBL25470130 | 0.63 | ALDH1A1 (0.54) | LIMK1CLK1ALDH1A1KDM4EMAPT | |
| SCHEMBL21263550 | 0.62 | LIMK1 (0.56) | LIMK1CLK1ALDH1A1KDM4EMAPT | |
| SCHEMBL24055645 | 0.62 | LMNA (0.44) | LIMK1CLK1ALDH1A1KDM4EMAPT | |
| SCHEMBL25470211 | 0.60 | NR4A2 (0.42) | LIMK1CLK1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |