Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810684 | 0.85 | EGLN1 (0.37) | LIMK1EGLN1CLK1ALDH1A1LMNA | |
| SCHEMBL1811891 | 0.72 | EGLN1 (0.72) | EGLN1SLC6A2 | |
| SCHEMBL1807613 | 0.72 | EGLN1 (0.48) | LIMK1EGLN1ALDH1A1LMNAKDM4E | |
| SCHEMBL1806922 | 0.69 | EGLN1 (0.46) | EGLN1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL1810830 | 0.66 | EGLN1 (0.46) | LIMK1EGLN1ALDH1A1KDM4EHTT | |
| SCHEMBL16919865 | 0.65 | LIMK1 (0.56) | LIMK1CLK1ALDH1A1LMNAKDM4E | |
| SCHEMBL16919879 | 0.65 | ALDH1A1 (0.49) | LIMK1CLK1ALDH1A1LMNAKDM4E | |
| SCHEMBL22373979 | 0.64 | LIMK1 (0.41) | LIMK1CLK1ALDH1A1LMNAKDM4E | |
| SCHEMBL16922508 | 0.62 | LIMK1 (0.66) | LIMK1CLK1LMNAKDM4EMAPT | |
| SCHEMBL16922286 | 0.62 | LIMK1 (0.45) | LIMK1CLK1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |