Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106906 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL18106895 | 0.84 | LPAR2 (0.67) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL18106896 | 0.83 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL18106909 | 0.83 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL15944972 | 0.81 | LPAR2 (0.71) | IRAK4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL18106900 | 0.79 | SMN1; SMN2 (0.48) | IRAK4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL18106907 | 0.77 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3597174 | 0.77 | IRAK4 (1.00) | IRAK4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30933802 | 0.76 | IRAK4 (0.70) | IRAK4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL25956566 | 0.76 | IRAK4 (0.70) | IRAK4SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742029-B1 | N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS | MERCK PATENT GMBH (DE) | 2016-10-05 | — | — | EP | claimed |