Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.68 |
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106888 | 0.87 | LPAR2 (0.57) | LPAR2IDO1DGAT1SOAT1MTOR | |
| SCHEMBL18106898 | 0.83 | LPAR2 (0.66) | LPAR2IDO1DGAT1SOAT1SMN1; SMN2 | |
| SCHEMBL18106906 | 0.82 | SMN1; SMN2 (0.63) | LPAR2IDO1SMN1; SMN2 | |
| SCHEMBL18106901 | 0.81 | PIN1 (0.51) | LPAR2CSNK1DKCNH2SMN1; SMN2RPS6KA2 | |
| SCHEMBL15944963 | 0.81 | LPAR2 (1.00) | LPAR2IDO1MTORDYRK1ADYRK1B | |
| SCHEMBL18106893 | 0.81 | TUBB4A (0.51) | LPAR2KDRSMN1; SMN2 | |
| SCHEMBL15947345 | 0.78 | LPAR2 (0.67) | LPAR2IDO1DGAT1MTORDYRK1A | |
| SCHEMBL18106907 | 0.77 | NPC1 (0.60) | MTORSMN1; SMN2 | |
| SCHEMBL15947325 | 0.77 | LPAR2 (0.66) | LPAR2IDO1DGAT1MTORDYRK1A | |
| SCHEMBL18106896 | 0.77 | NPC1 (0.60) | LPAR2MTORSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742029-B1 | N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS | MERCK PATENT GMBH (DE) | 2016-10-05 | — | — | EP | claimed |