Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181238 | 0.89 | — | — | |
| SCHEMBL2181544 | 0.89 | — | — | |
| SCHEMBL17361210 | 0.89 | — | — | |
| SCHEMBL4447804 | 0.80 | — | — | |
| SCHEMBL18106925 | 0.80 | — | — | |
| SCHEMBL920478 | 0.78 | — | — | |
| SCHEMBL50140 | 0.78 | — | — | |
| SCHEMBL19019958 | 0.78 | — | — | |
| SCHEMBL316188 | 0.78 | — | — | |
| SCHEMBL11612727 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178143-B1 | GENERATOR | ATSUMITEC KK (JP) | 2016-10-05 | — | — | EP | disclosed |
| CN-101779317-B | Generator | ATSUMITEC KK | 2013-03-20 | — | — | CN | disclosed |
| CN-101779317-A | generator | ATSUMITEC KK | 2010-07-14 | — | — | CN | disclosed |