Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18108341 | 1.00 | KCNH2 (0.42) | KCNH2NAAASIGMAR1DNM1EPHX1 | |
| SCHEMBL18108273 | 0.92 | SIGMAR1 (0.37) | NAAASIGMAR1HTTSMN1; SMN2CES2 | |
| SCHEMBL705023 | 0.87 | ALDH1A1 (0.32) | KCNH2SIGMAR1ALDH1A1 | |
| SCHEMBL18108052 | 0.84 | KCNH2 (0.42) | KCNH2NAAADNM1EPHX1EPHX2 | |
| SCHEMBL18108181 | 0.84 | KCNH2 (0.42) | KCNH2NAAADNM1EPHX1EPHX2 | |
| SCHEMBL18108163 | 0.84 | KCNH2 (0.42) | KCNH2NAAADNM1EPHX1EPHX2 | |
| SCHEMBL18108251 | 0.84 | KCNH2 (0.42) | KCNH2NAAADNM1EPHX1EPHX2 | |
| SCHEMBL18108369 | 0.84 | KCNH2 (0.42) | KCNH2NAAADNM1EPHX1EPHX2 | |
| SCHEMBL704482 | 0.83 | TP53 (0.35) | SIGMAR1ALDH1A1TP53KMT2A | |
| SCHEMBL707662 | 0.83 | ALDH1A1 (0.32) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884928-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| US-20160289354-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |